2018•PubMedRequires access

[Interleukin-6 in Psoriasis].

Wen Ming Wang, Hong Zhong Jin

Abstract

Psoriasis is a common,multifactorial,chronic inflammatory skin disease with an incompletely understood pathogenesis. A substantial number of inflammatory cytokines have been found to be elevated in psoriatic lesions,and the serum levels of a subset of these cytokines also correlate with the severity of psoriasis. Interleukin-6 is a multifunctional pro-inflammatory cytokine. Interleukin-6 is proved to be associated with many chronic inflammatory diseases and autoimmunity diseases such as psoriasis. This article reviews the relationship between interleukin-6 and psoriasis.

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Key concepts: Psoriasis, Medicine, Immunology, Cytokine, Pathogenesis, Autoimmunity, Interleukin, Disease