2020American Journal of Medicine and Medical SciencesOpen access

The Characteristic of the Immune Status at HIV-Infected Children with Acute Rhinosinusitis

N. U. Narzullayev, F. Ikramova

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Abstract

The immune status has been studied at 25 HIV-infected children with acute rhinosinusitis. The control group of comparison consisted of 14 practically healthy faces. At a HIV-infected patients with ARS has revealed deep infringements of the immune status, especially from the T-link of immunity and its subpopulations, and also frustration humoral an immunity link, suppression of proinflammatory cytokine IL-10 and increase proinflammatory IFN-γ. Under the influence of the spent treatment have not revealed certain changes from the immune status at patients. It is possible to ascertain only positive changes of maintenance IL-10 and parallel decrease IFN-γ in dynamics of treatment.

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What this paper is about

The immune status has been studied at 25 HIV-infected children with acute rhinosinusitis. The control group of comparison consisted of 14 practically healthy faces. At a HIV-infected patients with ARS has revealed deep infringements of the immune status, especially from the T-link of immunity and its subpopulations, and also frustration humoral an immunity link, suppression of proinflammatory cytokine IL-10 and increase proinflammatory IFN-γ. Under the influence of the spent treatment have not revealed certain changes from the immune status at patients. It is possible to ascertain only positive changes of maintenance IL-10 and parallel decrease IFN-γ in dynamics of treatment.

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Available abstract

The immune status has been studied at 25 HIV-infected children with acute rhinosinusitis. The control group of comparison consisted of 14 practically healthy faces. At a HIV-infected patients with ARS has revealed deep infringements of the immune status, especially from the T-link of immunity and its subpopulations, and also frustration humoral an immunity link, suppression of proinflammatory cytokine IL-10 and increase proinflammatory IFN-γ. Under the influence of the spent treatment have not revealed certain changes from the immune status at patients. It is possible to ascertain only positive changes of maintenance IL-10 and parallel decrease IFN-γ in dynamics of treatment.

Key concepts: Medicine, Proinflammatory cytokine, Immune status, Immune system, Immunology, Immunity, Human immunodeficiency virus (HIV), Humoral immunity

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