[Expression of cytokeratin(CK)7, CK8/18, CK19 and p40 in esophageal squamous cell carcinoma and their correlation with prognosis].
Zhe Yang, H Y Zhang, F Wang, Y H, Y Y Li, Hua Ling He, C Wang, S S Li
Abstract
Zhe Yang, H Y Zhang, F Wang, Y H, Y Y Li, Hua Ling He, C Wang, S S Li
Abstract
Low p40 expression and the expression of CK7 and CK8/18 cannot exclude poorly-differentiated ESCCs.CK7 and CK8/18 expression and low CK19 and p40 expression in the ESCCs are associated with lymph node metastasis and poor prognosis. Decreased expression of CK19 and positive expression of CK8/18 in ESCCs are independent prognostic markers.
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Low p40 expression and the expression of CK7 and CK8/18 cannot exclude poorly-differentiated ESCCs.CK7 and CK8/18 expression and low CK19 and p40 expression in the ESCCs are associated with lymph node metastasis and poor prognosis. Decreased expression of CK19 and positive expression of CK8/18 in ESCCs are independent prognostic markers.
Key concepts: Cytokeratin, Medicine, Esophageal squamous cell carcinoma, Lymph node metastasis, Lymph node, Pathology, Carcinoma, Basal cell