Un análisis sistemático de los pacientes con anemia en una clínica universitaria
Tuba-T Duman, Gülali Aktaş, Burcin M-Atak, M-Zahid Kocak, Haluk Şavlı
Abstract
Tuba-T Duman, Gülali Aktaş, Burcin M-Atak, M-Zahid Kocak, Haluk Şavlı
Abstract
Objectives. In this retrospective study, we aimed to present etiologies of anemia in patients treated in internal medicine clinic. Methods. Anemia patients’ characteristics and laboratory parameters were obtained from patients’ files and database of our clinic. Patients were divided into two groups; iron deficiency anemia and mixed or other causes of anemia groups. Results. Common anemia etiology in iron deficiency anemia group were gastrointestinal loss (42%), menstrual loss (45%), and in mixed or other causes of anemia group were malabsorption (37.3%), nutritional insufficiency (17.6%). Hb level was significantly and positively correlated with RBC, Htc, MCV, serum iron, transferrin saturation and negatively correlated with RDW in iron deficiency anemia group. Hb level was significantly and positively correlated with RBC, Htc, WBC and negatively correlated with RDW in mixed or other causes of anemia group. Neither of ferritin, PLT, vitamin B12 and folate levels were correlated with Hb level in study population. Conclusions. We suggest that transferrin saturation and serum iron are more valuable than serum ferritin level in determination of the iron deficiency anemia. In addition, MCV, RBC and RDW could be useful in differentiating of sole iron deficiency anemia from mixed or other causes of anemias.
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Objectives. In this retrospective study, we aimed to present etiologies of anemia in patients treated in internal medicine clinic. Methods. Anemia patients’ characteristics and laboratory parameters were obtained from patients’ files and database of our clinic. Patients were divided into two groups; iron deficiency anemia and mixed or other causes of anemia groups. Results. Common anemia etiology in iron deficiency anemia group were gastrointestinal loss (42%), menstrual loss (45%), and in mixed or other causes of anemia group were malabsorption (37.3%), nutritional insufficiency (17.6%). Hb level was significantly and positively correlated with RBC, Htc, MCV, serum iron, transferrin saturation and negatively correlated with RDW in iron deficiency anemia group. Hb level was significantly and positively correlated with RBC, Htc, WBC and negatively correlated with RDW in mixed or other causes of anemia group. Neither of ferritin, PLT, vitamin B12 and folate levels were correlated with Hb level in study population. Conclusions. We suggest that transferrin saturation and serum iron are more valuable than serum ferritin level in determination of the iron deficiency anemia. In addition, MCV, RBC and RDW could be useful in differentiating of sole iron deficiency anemia from mixed or other causes of anemias.
Key concepts: Anemia, Medicine, Ferritin, Transferrin saturation, Iron-deficiency anemia, Vitamin B12, Gastroenterology, Malabsorption