2019•PubMedOpen access
[The inhibition of accessory gene regulator C specific binding peptides on biofilm formation of Staphylococcus epidermidis on the surface of polyvinyl chloride in vitro].
Jichen Yang, Liangting Qiu, Yunchao Huang, Ya Chen, Sunyin Rao, Wenpeng Ruan, Guangqiang Zhao, Lianhua Ye
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Abstract
Objective: . Methods: . On this basis, the surface structure of the biofilm on the surface of PVC material was observed by scanning electron microscopy after 6, 12, 18, 24, and 30 hours of incubation with PVC material sheet. The thickness of the biofilm was observed by laser confocal microscopy after 6, 12, 18, and 24 hours of incubation with ATCC35984 strain. Results: <0.05). Conclusion: biofilm is dose-dependent. During the aggregation period, N1 can inhibit the biofilm formation by hindering the bacterial growth and aggregation. The inhibition effect on mature biofilm is not obvious.