2019Emerging infectious diseasesOpen access

Two Cases of Newly Characterized Neisseria Species, Brazil

Mustapha M. Mustapha, Ana Paula Silva de Lemos, M. Patrick Griffith, Daniel R. Evans, Ramon Marx, Elizabeth S.F. Coltro, Christian A. Siebra, Loeci Natalina Timm, Hamilton Ribeiro, Alessandro Martinez Monteiro, A. William Pasculle, Jane W. Marsh, Daria Van Tyne, Lee H. Harrison, Cláudio Tavares Sacchi

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Abstract

closest reported autochthonous human cases were in southwestern Hungary (5).E. multilocularis tapeworms have been reported in foxes in western and central Croatia (6) and likely is in eastern areas, such as Vukovar, because it was found in 17.9% of foxes and 14.3% of golden jackals in the region of Serbia directly across the Danube River from Vukovar (7).Since 2013, rabies vaccination has increased in Croatia, which might give the fox population an opportunity to expand and increase transmission of E. multilocularis tapeworms to humans, as noted in Switzerland (8).Correct diagnosis for this patient took 2.5 years because radiologic findings were inconsistent with cystic echinococcosis and clinicians assumed that was the only type of human echinococcosis in Croatia ( 9).This case highlights the need for clinicians to include alveolar echinococcosis in differential diagnosis of liver lesions.Imaging provides the first-line approach to such a diagnosis and serology provides strong complementary support.Our case also highlights the usefulness of considering pleural effusion and analyzing archival biopsies to retrospectively diagnose alveolar echinococcosis. About the Author

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closest reported autochthonous human cases were in southwestern Hungary (5).E. multilocularis tapeworms have been reported in foxes in western and central Croatia (6) and likely is in eastern areas, such as Vukovar, because it was found in 17.9% of foxes and 14.3% of golden jackals in the region of Serbia directly across the Danube River from Vukovar (7).Since 2013, rabies vaccination has increased in Croatia, which might give the fox population an opportunity to expand and increase transmission of E. multilocularis tapeworms to humans, as noted in Switzerland (8).Correct diagnosis for this patient took 2.5 years because radiologic findings were inconsistent with cystic echinococcosis and clinicians assumed that was the only type of human echinococcosis in Croatia ( 9).This case highlights the need for clinicians to include alveolar echinococcosis in differential diagnosis of liver lesions.Imaging provides the first-line approach to such a diagnosis and serology provides strong complementary support.Our case also highlights the usefulness of considering pleural effusion and analyzing archival biopsies to retrospectively diagnose alveolar echinococcosis. About the Author

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Available abstract

closest reported autochthonous human cases were in southwestern Hungary (5).E. multilocularis tapeworms have been reported in foxes in western and central Croatia (6) and likely is in eastern areas, such as Vukovar, because it was found in 17.9% of foxes and 14.3% of golden jackals in the region of Serbia directly across the Danube River from Vukovar (7).Since 2013, rabies vaccination has increased in Croatia, which might give the fox population an opportunity to expand and increase transmission of E. multilocularis tapeworms to humans, as noted in Switzerland (8).Correct diagnosis for this patient took 2.5 years because radiologic findings were inconsistent with cystic echinococcosis and clinicians assumed that was the only type of human echinococcosis in Croatia ( 9).This case highlights the need for clinicians to include alveolar echinococcosis in differential diagnosis of liver lesions.Imaging provides the first-line approach to such a diagnosis and serology provides strong complementary support.Our case also highlights the usefulness of considering pleural effusion and analyzing archival biopsies to retrospectively diagnose alveolar echinococcosis. About the Author

Key concepts: Neisseria meningitidis, Operon, Microbiology, Biology, Neisseria, Bacteremia, Neisseriaceae, Genetics

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