S Y Wang, Qing Xue, Yun Zhou, Lei Yin
Abstract
Metformin could down-regulate the mRNA expression level of aromatase in the uterine leiomyoma cells. These results indicate that metformin may inhibit the local estrogen synthesis and therefore suppress the development of uterine leiomyoma.
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Metformin could down-regulate the mRNA expression level of aromatase in the uterine leiomyoma cells. These results indicate that metformin may inhibit the local estrogen synthesis and therefore suppress the development of uterine leiomyoma.
Key concepts: Myometrium, Uterine leiomyoma, Aromatase, Leiomyoma, Endocrinology, Cholesterol side-chain cleavage enzyme, Internal medicine, Estrogen