2020Journal of Clinical MicrobiologyOpen access

Human Blastomycosis in South Africa Caused byBlastomyces percursusandBlastomyces emzantsisp. nov., 1967 to 2014

Tsidiso G. Maphanga, Monica Birkhead, José Fernando Muñoz, Mushal Allam, Thokozile G. Zulu, Christina A. Cuomo, Ilan Steven Schwartz, Arshad Ismail, Serisha D. Naicker, Ruth S. Mpembe, Craig Corcoran, Sybren de Hoog, Chris Richard Kenyon, Andrew M. Borman, John Frean, Nelesh Premapragasan Govender

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Abstract

We reevaluated 20 cases of blastomycosis diagnosed in South Africa between 1967 and 2014, with Blastomyces dermatitidis considered to be the etiological agent, in light of newly described species and the use of more advanced technologies. In addition to histopathological and/or culture-based methods, all 20 isolates were phenotypically and genotypically characterized, including multilocus typing of five genes and whole-genome sequencing.

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What this paper is about

We reevaluated 20 cases of blastomycosis diagnosed in South Africa between 1967 and 2014, with Blastomyces dermatitidis considered to be the etiological agent, in light of newly described species and the use of more advanced technologies. In addition to histopathological and/or culture-based methods, all 20 isolates were phenotypically and genotypically characterized, including multilocus typing of five genes and whole-genome sequencing.

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Available abstract

We reevaluated 20 cases of blastomycosis diagnosed in South Africa between 1967 and 2014, with Blastomyces dermatitidis considered to be the etiological agent, in light of newly described species and the use of more advanced technologies. In addition to histopathological and/or culture-based methods, all 20 isolates were phenotypically and genotypically characterized, including multilocus typing of five genes and whole-genome sequencing.

Key concepts: Blastomyces, Blastomycosis, Blastomyces dermatitidis, Microbiology, Biology, Virology, Immunology

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Human Blastomycosis in South Africa Caused byBlastomyces percursusandBlastomyces emzantsisp. nov., 1967 to 2014 — Research Paper | ScholarLens