GENDER SENSITIVE ANALYSIS OF CATHETER-ASSOCIATED URINE INFECTIONS IN CHILDREN WITH SURGICAL AND SOMATIC PATHOLOGY REQURING INTENSIVE THERAPY

Introduction. Every third patient of the intensive care unit being for more than 3 days in the unit and having urinary catheter has signs of urinary tract inflammation.Purpose of research is to improve the results of treatment of patients with nosocomial urinary tract infection through gender-sensitive analysis of its pathogenesis, diagnostic criteria, methods of prevention and treatment.Materials and methods. 98 patients of the intensive care unit of the Lviv Regional Children’s Clinical Hospital "OKHMATDYT" aged 1-18 years were tested. The 1st group amounting to 49 children consisted of patients with purulent surgical pathology; urinary bladder catheterization to children in this group was performed under surgical conditions. The 2nd group amounting to 49 children consisted of patients with somatic pathology; urinary bladder catheterization to patients in this group was performed in the intensive care unit.Results and discussion. The results of our research showed a significantly higher rate of development of catheter-associated urinary tract infections that occur in the 2nd group of male patients (19%) than in the 1st group (31%) on the third day of urinary bladder catheterization, р≤0,005. On the third day of catheterization, the frequency of catheter-associated urinary tract infections in the 2nd group of female patients was significantly higher (40%) compared to the 1st group of female patients (18%), p≤0,005. We did not find significant differences in the gender-sensitive distribution of catheter-associated infections in children requiring intensive therapy.Conclusions. Thus, we observed a significantly higher rate of development of catheter-associated urinary tract infections in males and females in the 2nd group than in the 1st group, which is likely to be associated with catheterization conditions. We also observed a higher frequency of catheter-associated urinary tract infections in the 1st group of females compared to the 1st group of males which can be linked to the anatomical features of the former. In our opinion, initiating antibacterial therapy of catheter-associated urinary tract infections earlier than on the third day of bladder catheterization and prior to obtaining results of bacteriological examination of urine is unreasonable and it increases the antibiotic resistance of microorganisms of the intensive care unit.