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2019•Acta OphthalmologicaRequires access

Optic nerve complications after irradiation

Alexandre Matet

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Abstract

Abstract Optic neuropathy is a dramatic complication of ocular irradiation, usually leading to complete visual loss. This presentation will review the putative mechanisms, including direct neurotoxicity and indirect optic nerve head ischemic damage secondary to radiation microangiopathy; the spectrum of clinical manifestations; and available therapies for optic nerve complications after ocular irradiation.

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What this paper is about

Abstract Optic neuropathy is a dramatic complication of ocular irradiation, usually leading to complete visual loss. This presentation will review the putative mechanisms, including direct neurotoxicity and indirect optic nerve head ischemic damage secondary to radiation microangiopathy; the spectrum of clinical manifestations; and available therapies for optic nerve complications after ocular irradiation.

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Available abstract

Abstract Optic neuropathy is a dramatic complication of ocular irradiation, usually leading to complete visual loss. This presentation will review the putative mechanisms, including direct neurotoxicity and indirect optic nerve head ischemic damage secondary to radiation microangiopathy; the spectrum of clinical manifestations; and available therapies for optic nerve complications after ocular irradiation.

Key concepts: Optic nerve, Medicine, Complication, Optic neuropathy, Neurotoxicity, Microangiopathy, Surgery, Presentation (obstetrics)

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