2018Unpublished venueRequires access

The Effect of CAR-T Cell Therapy in The Treatment of Cancer, And Associated Side Effects

Khalifa O. Gnieber

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Abstract

When the immune system is functioning normally, immune cells move around the body looking for things that don’t belong, like bacteria and viruses. These immune cells search for invaders using “receptors”. When receptors find invaders in the body, special immune cells come in to destroy them; these cells are called cytotoxic T cells. Unfortunately, cancer cells are often able to hide from immune cells, which is why the cancer cells can grow out of control. Immunotherapy is a cancer treatment intended to make the body’s immune system able to detect and destroy cancer cells. Immune checkpoint inhibitors have been a successful immunotherapy approach because it pushes the immune system into high gear to fight cancer.

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What this paper is about

When the immune system is functioning normally, immune cells move around the body looking for things that don’t belong, like bacteria and viruses. These immune cells search for invaders using “receptors”. When receptors find invaders in the body, special immune cells come in to destroy them; these cells are called cytotoxic T cells. Unfortunately, cancer cells are often able to hide from immune cells, which is why the cancer cells can grow out of control. Immunotherapy is a cancer treatment intended to make the body’s immune system able to detect and destroy cancer cells. Immune checkpoint inhibitors have been a successful immunotherapy approach because it pushes the immune system into high gear to fight cancer.

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Available abstract

When the immune system is functioning normally, immune cells move around the body looking for things that don’t belong, like bacteria and viruses. These immune cells search for invaders using “receptors”. When receptors find invaders in the body, special immune cells come in to destroy them; these cells are called cytotoxic T cells. Unfortunately, cancer cells are often able to hide from immune cells, which is why the cancer cells can grow out of control. Immunotherapy is a cancer treatment intended to make the body’s immune system able to detect and destroy cancer cells. Immune checkpoint inhibitors have been a successful immunotherapy approach because it pushes the immune system into high gear to fight cancer.

Key concepts: Immune system, Cytotoxic T cell, Immunotherapy, Cancer cell, Cancer immunotherapy, Cancer, Immune checkpoint, Immunology

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