EFFICIENCY OF IN-VITRO ANTIBACTERIAL ACTIVITY OF SYZYGIUM CUMINI PHENOLIC EXTRACT FROM LEAVES

Objective: The fundamental objective of this analysis is to assess the potential effect of the phenolic plant extract from Syzygium cumini against bacterial culture. This response indicates the antibacterial properties of the phenolic extract of the plant which can be exploited as a feasible antibacterial agent. Methods: The antibacterial activity of the phenolic-rich extract was tested against human pathogenic bacteria Staphylococcus aureus and Pseudomonas aeruginosa using the disc diffusion method and minimum inhibitory concentration. Preliminary phytochemical studies revealed the presence of alkaloids, flavonoids, polyphenols, glycosides, terpenoid, and tannins. Results: The phenolic extract showed potent inhibitory activity against Gram-positive bacterium S. aureus and Gram-negative bacterium P. aeruginosa. The zone of inhibition obtained in the antibacterial assay was scrutinized, and the results obtained were analyzed in terms of the antibacterial activity. Conclusion: Hereby, inferring from the experimental outcomes, the phenolic plant extract of S. cumini can be used as an effective antibacterial agent. Keywords: Polyphenol, Antibacterial activity, Disc diffusion, Syzygium cumini.