2019European Journal of Organic ChemistryOpen access

Regioselective Alkylation of Pyridinium Riboses

Farbod Salahi, Olaf Wiest

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Abstract

The nucleophilic addition of alkyl, benzyl, and allyl organozinc reagents to protected pyridinium riboses proceeds under mild conditions and with yields of >90% in several cases and complete regioselectivity for the 4-position.

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What this paper is about

The nucleophilic addition of alkyl, benzyl, and allyl organozinc reagents to protected pyridinium riboses proceeds under mild conditions and with yields of >90% in several cases and complete regioselectivity for the 4-position.

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Available abstract

The nucleophilic addition of alkyl, benzyl, and allyl organozinc reagents to protected pyridinium riboses proceeds under mild conditions and with yields of >90% in several cases and complete regioselectivity for the 4-position.

Key concepts: Regioselectivity, Pyridinium, Chemistry, Alkylation, Reagent, Nucleophile, Alkyl, Pyridinium Compounds

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