Regioselective Alkylation of Pyridinium Riboses
Farbod Salahi, Olaf Wiest
Abstract
Farbod Salahi, Olaf Wiest
Abstract
The nucleophilic addition of alkyl, benzyl, and allyl organozinc reagents to protected pyridinium riboses proceeds under mild conditions and with yields of >90% in several cases and complete regioselectivity for the 4-position.
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The nucleophilic addition of alkyl, benzyl, and allyl organozinc reagents to protected pyridinium riboses proceeds under mild conditions and with yields of >90% in several cases and complete regioselectivity for the 4-position.
Key concepts: Regioselectivity, Pyridinium, Chemistry, Alkylation, Reagent, Nucleophile, Alkyl, Pyridinium Compounds