2017•PubMedOpen access

[Immunological mechanism of prednisone in the treatment of infantile spasm].

Hui Chen, Jianmin Zhong, Zhaoshi Yi, Jian Zha, Yong Chen, Lan-Yun Cai

Abstract

OBJECTIVE: To investigate the immunological mechanism of prednisone in the treatment of infantile spasm (IS) by evaluating the immune function of IS children before and after treatment. METHODS: ). The clinical outcome and electroencephalographic findings were evaluated for all IS children after prednisone treatment. RESULTS: T lymphocytes (P<0.05). CONCLUSIONS: IS children have immune dysfunction. Prednisone can control seizures in IS children, possibly by regulating and improving immune dysfunction.

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Key concepts: Prednisone, Medicine, Internal medicine, CD8, Gastroenterology, Immune system, Antibody, Endocrinology