2019•International Journal of Advances in MedicineOpen access

The impact of intravenous thrombolysis in acute ischemic stroke in National Medical College, Kolkata: initial experience

Saikat Ghosh, Manoj Kr. Mahata, Sarbajit Das, K. Ghosh, Ramesh Bhattacharya, G Mondal, Sumit Deb

Abstract

Background: Acute ischemic stroke is a potentially treatable condition, if left untreated, lead to mortality and morbidity. This study was conducted to study clinical profile of patients with acute ischemic stroke receiving intravenous thrombolysis (r-TPA-alteplase) and to measure the outcome of thrombolysis.Methods: Retrospective observational study of 54 patients who underwent thrombolysis for acute ischemic stroke at National Medical College, Kolkata over a period of one year.Results: There was statistically significant improvement in NIHSS (p value-0.000) after intravenous thrombolysis.Conclusions: IV thrombolysis is feasible for AIS in governmental hospital in India.

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Key concepts: Thrombolysis, Medicine, Observational study, Acute stroke, Stroke (engine), Emergency medicine, Ischemic stroke, Retrospective cohort study