2018PubMedOpen access

[Elevated Fas expression is related to increased apoptosis of circulating CD8(+)T cell in patients with hepatocellular carcinoma].

Guo Cl, Bi Ym, Z Liu, Yan Xu, Sun Yx, Wang Qc

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Abstract

The proportion of CD8(+)T lymphocytes in peripheral blood of patients with HCC is higher than that of healthy controls, but the proportion of CD8(+)T lymphocyte apoptosis based on Fas/FasL pathway increased, which may be an important mechanism for tumor cell immune escape.

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What this paper is about

The proportion of CD8(+)T lymphocytes in peripheral blood of patients with HCC is higher than that of healthy controls, but the proportion of CD8(+)T lymphocyte apoptosis based on Fas/FasL pathway increased, which may be an important mechanism for tumor cell immune escape.

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Available abstract

The proportion of CD8(+)T lymphocytes in peripheral blood of patients with HCC is higher than that of healthy controls, but the proportion of CD8(+)T lymphocyte apoptosis based on Fas/FasL pathway increased, which may be an important mechanism for tumor cell immune escape.

Key concepts: CD8, Hepatocellular carcinoma, Medicine, Internal medicine, Cirrhosis, Gastroenterology, Apoptosis, Flow cytometry

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[Elevated Fas expression is related to increased apoptosis of circulating CD8(+)T cell in patients with hepatocellular carcinoma]. — Research Paper | ScholarLens