2019Science and Technology Facilities CouncilOpen access

GISANS directed to study lipid bilayer structures on nanowire arrays

Professor Tommy Nylander, Sarah E. Rogers, Miss Karolina Mothander, Professor Adrian Rennie, Judith E. Houston

Open full text 0 citations

Abstract

Nanowires are increasingly being used in life science to interact with living cells, for example as nanometer probes. The interaction between the cell membrane, i.e. a lipid bilayer, and the nanowires is not fully understood. In this proposal we will study the structure of the lipid bilayer with time-of-flight (TOF) grazing incident small angle neutron scattering (GISANS). We will also use the lipid bilayer on nanowires as curved model membrane and anchor membrane proteins in the bilayer. This is done to study the how the membrane proteins are affected by the curvature of the lipid bilayer.

About this research paper

What this paper is about

Nanowires are increasingly being used in life science to interact with living cells, for example as nanometer probes. The interaction between the cell membrane, i.e. a lipid bilayer, and the nanowires is not fully understood. In this proposal we will study the structure of the lipid bilayer with time-of-flight (TOF) grazing incident small angle neutron scattering (GISANS). We will also use the lipid bilayer on nanowires as curved model membrane and anchor membrane proteins in the bilayer. This is done to study the how the membrane proteins are affected by the curvature of the lipid bilayer.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Nanowires are increasingly being used in life science to interact with living cells, for example as nanometer probes. The interaction between the cell membrane, i.e. a lipid bilayer, and the nanowires is not fully understood. In this proposal we will study the structure of the lipid bilayer with time-of-flight (TOF) grazing incident small angle neutron scattering (GISANS). We will also use the lipid bilayer on nanowires as curved model membrane and anchor membrane proteins in the bilayer. This is done to study the how the membrane proteins are affected by the curvature of the lipid bilayer.

Key concepts: Lipid bilayer, Bilayer, Membrane curvature, Lipid bilayer mechanics, Nanowire, Model lipid bilayer, Lipid bilayer phase behavior, Membrane

Related papers

Back to paper searchBrowse research topicsOriginal source
GISANS directed to study lipid bilayer structures on nanowire arrays — Research Paper | ScholarLens