2018•PubMedRequires access

[Effects of aminooxyacetic acid on the learning and memory ability and its possible mechanism in rats with chronic alcoholism].

Haozhi Qin, Hong-Bo Jiang, Xuan Dai, Yadi Huang, Xiao-Qiu Luo, Ruiling Zhang, Ailin Du

Abstract

OBJECTIVE: To investigate the effects of aminooxyacetic acid (AOAA) on learning and memory ability and possible mechanisms in rats with chronic alcoholism. METHODS: S, the activity of ATP enzyme and the expression of 5-HT in hippocampus were measured. RESULTS: <0.01). CONCLUSIONS: S, the mitochondrial enzyme activity and the expression of 5-HT in hippocampus.

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Available abstract

Key concepts: Aminooxyacetic acid, Hippocampus, Intraperitoneal injection, Saline, Internal medicine, Morris water navigation task, Water maze, Endocrinology