2017•PubMedOpen access

Evidence for Idarucizumab (Praxbind) in the Reversal Of the Direct Thrombin Inhibitor Dabigatran: Review Following the RE-VERSE AD Full Cohort Analysis.

Timothy C. Hutcherson, Nicole E. Cieri‐Hutcherson, Rajvi Bhatt

Abstract

Idarucizumab is the first reversal agent approved for the direct thrombin inhibitor dabigatran. The authors summarize the findings from the clinical trial series and describe case reports, post-marketing data, and ongoing studies.

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Available abstract

Key concepts: Idarucizumab, Dabigatran, Direct thrombin inhibitor, Medicine, Discovery and development of direct thrombin inhibitors, Thrombin, Pharmacology, Internal medicine