2017•PubMedRequires access

[Hydrogen can alleviate post-cardiac arrest myocardium injury in rabbits].

Jingao Wang, Jiyan Lin, Minwei Zhang, Yujing He, Xiaowen Pan, Chengbin Yang, Dongmei Cai

Abstract

OBJECTIVE: ) on myocardium injury post-cardiac arrest (CA) in rabbits. METHODS: treatment group. Air was given to rabbits in control group instead. The survival rate of rabbits was analyzed. Heart rate, ventricular premature beat frequency, and the levels of blood samples cardiac troponin I (cTnI), left ventricular ejection fraction (LVEF), B-type natriuretic peptide (BNP), and blood lactic acid (Lac) were collected before CA and after ROSC in all rabbits. Rabbits were sacrificed and microstructure injury was observed by electric microscope after ROSC 72 hours. RESULTS: treatment group at 72 hours after ROSC. CONCLUSIONS: alleviates cardiac dysfunction and myocardial injury after CPR.

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Key concepts: Medicine, Cardiopulmonary resuscitation, Ejection fraction, Resuscitation, Anesthesia, Troponin I, Heart rate, Survival rate