1999•Unpublished venueRequires access

Glycopeptide and Oligosaccharide Libraries

Phaedria M. St. Hilaire, Morten Meldal

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Abstract

This chapter contains sections titled: Parallel Arrays versus Libraries of Compounds Proteins Recognising Carbohydrates The Carbohydrate Ligands Supports for Solid-Phase Libraries Analytical Tools for Oligosaccharide and Glycopeptide Libraries Introduction to Array and Library Synthesis of Oligosaccharides Parallel Synthesis of Oligosaccharide Arrays Synthesis of Oligosaccharide Libraries Glycopeptide Templates as Oligosaccharide Mimetics Parallel Synthesis of Glycopeptide Arrays Preparation and AnaIysis of Solid-Phase Clycopeptide Template Libraries Screening of a Solid-Phase Glycopeptide Library Conclusions Acknowledgements References

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What this paper is about

This chapter contains sections titled: Parallel Arrays versus Libraries of Compounds Proteins Recognising Carbohydrates The Carbohydrate Ligands Supports for Solid-Phase Libraries Analytical Tools for Oligosaccharide and Glycopeptide Libraries Introduction to Array and Library Synthesis of Oligosaccharides Parallel Synthesis of Oligosaccharide Arrays Synthesis of Oligosaccharide Libraries Glycopeptide Templates as Oligosaccharide Mimetics Parallel Synthesis of Glycopeptide Arrays Preparation and AnaIysis of Solid-Phase Clycopeptide Template Libraries Screening of a Solid-Phase Glycopeptide Library Conclusions Acknowledgements References

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Available abstract

This chapter contains sections titled: Parallel Arrays versus Libraries of Compounds Proteins Recognising Carbohydrates The Carbohydrate Ligands Supports for Solid-Phase Libraries Analytical Tools for Oligosaccharide and Glycopeptide Libraries Introduction to Array and Library Synthesis of Oligosaccharides Parallel Synthesis of Oligosaccharide Arrays Synthesis of Oligosaccharide Libraries Glycopeptide Templates as Oligosaccharide Mimetics Parallel Synthesis of Glycopeptide Arrays Preparation and AnaIysis of Solid-Phase Clycopeptide Template Libraries Screening of a Solid-Phase Glycopeptide Library Conclusions Acknowledgements References

Key concepts: Glycopeptide, Oligosaccharide, Solid-phase synthesis, Chemistry, Template, Biochemistry, Combinatorial chemistry, Computer science

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