2018PubMedRequires access

The efficacy of febuxostat and allopurinol in the treatment of gout with hyperuricemia.

Sufang Wang

Open publisher page 14 citations

Abstract

The aim of this research work was to observe and analyze the efficacy of febuxostat and allopurinol in the treatment of gout with hyperuricemia. The 160 patients who has been diagnosed with gout and hyperuricemia in our hospital were selected as research objects. They were randomly divided into research group and control group, each containing 80. The control group received conventional allopurinol treatment, while the research group was treated with febuxostat. Then, the treatment efficacy was compared between the two groups. Through comparison of blood uric acid levels between the two groups after treatment, it can be known that improvement was more significant in the research group, P<0.05. The adverse reaction rate in the research group was significantly lower, P<0.05. For patients with gout and hyperuricemia, febuxostat therapy has better efficacy than that of allopurinol.

About this research paper

What this paper is about

The aim of this research work was to observe and analyze the efficacy of febuxostat and allopurinol in the treatment of gout with hyperuricemia. The 160 patients who has been diagnosed with gout and hyperuricemia in our hospital were selected as research objects. They were randomly divided into research group and control group, each containing 80. The control group received conventional allopurinol treatment, while the research group was treated with febuxostat. Then, the treatment efficacy was compared between the two groups. Through comparison of blood uric acid levels between the two groups after treatment, it can be known that improvement was more significant in the research group, P<0.05. The adverse reaction rate in the research group was significantly lower, P<0.05. For patients with gout and hyperuricemia, febuxostat therapy has better efficacy than that of allopurinol.

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Available abstract

The aim of this research work was to observe and analyze the efficacy of febuxostat and allopurinol in the treatment of gout with hyperuricemia. The 160 patients who has been diagnosed with gout and hyperuricemia in our hospital were selected as research objects. They were randomly divided into research group and control group, each containing 80. The control group received conventional allopurinol treatment, while the research group was treated with febuxostat. Then, the treatment efficacy was compared between the two groups. Through comparison of blood uric acid levels between the two groups after treatment, it can be known that improvement was more significant in the research group, P<0.05. The adverse reaction rate in the research group was significantly lower, P<0.05. For patients with gout and hyperuricemia, febuxostat therapy has better efficacy than that of allopurinol.

Key concepts: Febuxostat, Hyperuricemia, Allopurinol, Gout, Medicine, Uric acid, Internal medicine, Adverse effect

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The efficacy of febuxostat and allopurinol in the treatment of gout with hyperuricemia. — Research Paper | ScholarLens