[Research on Relation of Platelet Aggregation Rate with Platelet Concentration in Platelet-Rich Plasma'].

OBJECTIVE: To explore the effect of platelet concentration in platelet-rich plasma (PRP)' on platelet aggregation rate, to determine the allowed range of inducer adenosine diphosphate (ADP: 5.0 µmol/L, ADP: 1.5 µmol/L) and arachidonic acid (AA: 500.0 µg/ml) for platelet concentration in platelet aggregation rate. METHODS: The venous blood samples of 72 healthy persons with citrate anticoagulation were selected and divided into groups, every 12 cases were mixed for each group. After the samples were mixed, different levels of platelet concentrations were prepared, and platelet aggregation rate of 6 groups with different platelet concentrations by ADP and AA inducer were detected by Helena platelet aggregation analyzer respectively. RESULTS: /L and AA 500 µg/ml and ADP 15 µmol/L were used for induction, the changes of platelet aggregation rate of different concentrations of platelet was slow, less volatile and more stable. CONCLUSION: /L.