[Effects of caspase-1 inhibitor VX765 on cold-restraint stress-induced acute gastric ulcer in mice].
Shiqing Zheng, XIANFEI HONG, T S Chen, Pan Luo, Shang-zhi Xiao
Abstract
Shiqing Zheng, XIANFEI HONG, T S Chen, Pan Luo, Shang-zhi Xiao
Abstract
VX765 can effectively inhibit the activation of caspase-1, reduce production of inflammatory factor, and alleviate inflammatory response, which have protective effects on gastric mucosa of mice with cold-restraint stress-induced acute gastric ulcer.
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VX765 can effectively inhibit the activation of caspase-1, reduce production of inflammatory factor, and alleviate inflammatory response, which have protective effects on gastric mucosa of mice with cold-restraint stress-induced acute gastric ulcer.
Key concepts: Ulcer index, Intraperitoneal injection, Gastric mucosa, Medicine, Saline, Internal medicine, Tumor necrosis factor alpha, Pharmacology