2017•PubMedRequires access

[Effects of caspase-1 inhibitor VX765 on cold-restraint stress-induced acute gastric ulcer in mice].

Shiqing Zheng, XIANFEI HONG, T S Chen, Pan Luo, Shang-zhi Xiao

Open publisher page 5 citations

Abstract

VX765 can effectively inhibit the activation of caspase-1, reduce production of inflammatory factor, and alleviate inflammatory response, which have protective effects on gastric mucosa of mice with cold-restraint stress-induced acute gastric ulcer.

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What this paper is about

VX765 can effectively inhibit the activation of caspase-1, reduce production of inflammatory factor, and alleviate inflammatory response, which have protective effects on gastric mucosa of mice with cold-restraint stress-induced acute gastric ulcer.

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OpenAlex reports 5 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

VX765 can effectively inhibit the activation of caspase-1, reduce production of inflammatory factor, and alleviate inflammatory response, which have protective effects on gastric mucosa of mice with cold-restraint stress-induced acute gastric ulcer.

Key concepts: Ulcer index, Intraperitoneal injection, Gastric mucosa, Medicine, Saline, Internal medicine, Tumor necrosis factor alpha, Pharmacology

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[Effects of caspase-1 inhibitor VX765 on cold-restraint stress-induced acute gastric ulcer in mice]. — Research Paper | ScholarLens