Ichthyosiform sarcoidosis and systemic involvement.

Sarcoidosis is a systemic disease that can be suspected based on cutaneous findings and confirmed using diagnostic testing such as biopsy and laboratory or radiographic studies. We report the case of a 66-year-old black woman with ichthyosiform sarcoidosis (IS) on the lower extremities. Ichthyosiform sarcoidosis is a rare variant of cutaneous sarcoidosis that is frequently associated with further internal involvement. We review this uncommon presentation of sarcoidosis along with other cases reported in the literature to determine the organ systems most commonly affected.