2019Avicenna BulletinOpen access

SOFT TISSUE SARCOMA: A MODERN VIEW TO THE PROBLEM

Valeriy Vasilievich Benberin, Beybit Tlektesovich Bayzakov, Nasrulla Shanazarov, С В Зинченко

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Abstract

The review discusses the distribution and treatment of soft tissue sarcoma. Thus, about 10,000 new patients are registered in the Russian Federation every year; the incidence is 30 cases per 1 million populations. The age range of soft tissue sarcoma is on average 56-65 years with a peak in the age of 80-90 years. Fundamental aspects of the issue are illuminated. Thus, there are more than 100 histological types of soft tissue sarcoma; the most common include undifferentiated sarcomas, liposarcomas, leiosarcomas, synovial sarcomas and malignant tumor of peripheral nerve membranes. Considered issues of diagnostic criteria. According to the recommendations of the WHO to improve the accuracy of diagnosis in soft tissue sarcoma, the traditional histopathological examination should be supplemented with immunohistochemical and molecular methods. Studied modern approaches to the treatment of malignancies. One such approach is «Oncology Control», which means minimizing the risk of recurrence at the local and systemic level. Keywords: Sarcoma, soft tissue sarcoma , diagnostic criteria of sarcoma, soft tissue sarcoma treatment standards, , soft tissue sarcoma classification.

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The review discusses the distribution and treatment of soft tissue sarcoma. Thus, about 10,000 new patients are registered in the Russian Federation every year; the incidence is 30 cases per 1 million populations. The age range of soft tissue sarcoma is on average 56-65 years with a peak in the age of 80-90 years. Fundamental aspects of the issue are illuminated. Thus, there are more than 100 histological types of soft tissue sarcoma; the most common include undifferentiated sarcomas, liposarcomas, leiosarcomas, synovial sarcomas and malignant tumor of peripheral nerve membranes. Considered issues of diagnostic criteria. According to the recommendations of the WHO to improve the accuracy of diagnosis in soft tissue sarcoma, the traditional histopathological examination should be supplemented with immunohistochemical and molecular methods. Studied modern approaches to the treatment of malignancies. One such approach is «Oncology Control», which means minimizing the risk of recurrence at the local and systemic level. Keywords: Sarcoma, soft tissue sarcoma , diagnostic criteria of sarcoma, soft tissue sarcoma treatment standards, , soft tissue sarcoma classification.

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Available abstract

The review discusses the distribution and treatment of soft tissue sarcoma. Thus, about 10,000 new patients are registered in the Russian Federation every year; the incidence is 30 cases per 1 million populations. The age range of soft tissue sarcoma is on average 56-65 years with a peak in the age of 80-90 years. Fundamental aspects of the issue are illuminated. Thus, there are more than 100 histological types of soft tissue sarcoma; the most common include undifferentiated sarcomas, liposarcomas, leiosarcomas, synovial sarcomas and malignant tumor of peripheral nerve membranes. Considered issues of diagnostic criteria. According to the recommendations of the WHO to improve the accuracy of diagnosis in soft tissue sarcoma, the traditional histopathological examination should be supplemented with immunohistochemical and molecular methods. Studied modern approaches to the treatment of malignancies. One such approach is «Oncology Control», which means minimizing the risk of recurrence at the local and systemic level. Keywords: Sarcoma, soft tissue sarcoma , diagnostic criteria of sarcoma, soft tissue sarcoma treatment standards, , soft tissue sarcoma classification.

Key concepts: Synovial sarcoma, Sarcoma, Soft tissue, Soft tissue sarcoma, Medicine, Malignant peripheral nerve sheath tumor, Pathology, Immunohistochemistry

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