2013•Practical Journal of Cardiac Cerebral Pneumal and Vascular DiseaseRequires access
Effect Observation of L-carnitine in Treatment of Chronic Heart Failure
Zeng Chao-fu
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Abstract
Objective To observe the clinical efficacy of L-carnitine in treatment of patients with chronic heart failure(CHF).Methods 100 cases of CHF patients,which were randomly divided into control group and treatment group,with 50 cases in each.The control group was given conventional strong heart,diuretic,vasodilator based anti heart failure treatment;the treatment group based on the use of L-carnitine intravenously.After 1 weeks of treatment and cardiac ultrasound detection of heart function,6min walk test 6min walking maximum distance before treatment and curative effects of two groups were observed.Results Two groups of left ventricular end-systolic volume after treatment(LVESV),left ventricular end-diastolic volume(LVEDV),left ventricular ejection fraction(LVEF),6min walking distance,the differences were statistically significant(P0.05).The total effective rate of treatment group was 92%,the total effective rate of control group was 70%,compared with two groups of curative effect,the difference was statistically significant(P0.05).Conclusion The curative effect of L-carnitine in treatment of CHF was significant,and can significantly improve heart function of patients with.