2009•Problems of EndocrinologyOpen access

New evidence for the pathogenesis of obesity: adipokines are adipose tissue hormone

А В Косыгина, O. V. Vasyukova

Abstract

In recent years, the independent role of adipose tissue in the pathogenesis of obesity and related complications has been actively discussed. Adipose tissue is also a key factor in the development and progression of insulin resistance. Among adipokines secreted by adipose tissue and influencing the development of insulin resistance and metabolic disorders, the most studied are leptin, adiponectin, resistin, visfatin. These adipokines are dedicated to this review.

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Key concepts: Adipokine, Adipose tissue, Pathogenesis, Medicine, Hormone, Obesity, Endocrinology, Leptin