2019•Obstetrical & Gynecological SurveyRequires access

Dual Trigger With Gonadotropin Releasing Hormone Agonist and Human Chorionic Gonadotropin Significantly Improves Live Birth Rate for Women With Diminished Ovarian Reserve

Ming-Huei Lin, Frank Shao-Ying Wu, Yuh‐Ming Hwu, Robert Kuo‐Kuang Lee, Ryh-Sheng Li, Sheng‐Hsiang Li

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Abstract

(Abstracted from Reprod Biol Endocrinol 2019;17:7) As the prevalence of fertility treatment increases, research into managing “diminished ovarian reserve” (DOR) remains a challenge. A “dual trigger” consisting of a gonadotropin hormone–releasing hormone agonist (GnRH-a) in combination with a reduced dose of human chorionic gonadotropin (hCG) showed robust evidence of increased pregnancy and live birth rate without ovarian hyperstimulation in in vitro fertilization (IVF) cycles for high responders.

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(Abstracted from Reprod Biol Endocrinol 2019;17:7) As the prevalence of fertility treatment increases, research into managing “diminished ovarian reserve” (DOR) remains a challenge. A “dual trigger” consisting of a gonadotropin hormone–releasing hormone agonist (GnRH-a) in combination with a reduced dose of human chorionic gonadotropin (hCG) showed robust evidence of increased pregnancy and live birth rate without ovarian hyperstimulation in in vitro fertilization (IVF) cycles for high responders.

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OpenAlex reports 5 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

(Abstracted from Reprod Biol Endocrinol 2019;17:7) As the prevalence of fertility treatment increases, research into managing “diminished ovarian reserve” (DOR) remains a challenge. A “dual trigger” consisting of a gonadotropin hormone–releasing hormone agonist (GnRH-a) in combination with a reduced dose of human chorionic gonadotropin (hCG) showed robust evidence of increased pregnancy and live birth rate without ovarian hyperstimulation in in vitro fertilization (IVF) cycles for high responders.

Key concepts: Medicine, Gonadotropin-releasing hormone agonist, Human chorionic gonadotropin, Agonist, In vitro fertilisation, Ovarian reserve, Gonadotropin, Live birth

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Dual Trigger With Gonadotropin Releasing Hormone Agonist and Human Chorionic Gonadotropin Significantly Improves Live Birth Rate for Women With Diminished Ovarian Reserve — Research Paper | ScholarLens