2019•JAAD Case ReportsOpen access

Hailey-Hailey disease treated successfully with naltrexone and magnesium

Ali Alajmi, Abdulhadi H. Jfri, Audrey Lovett

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Abstract

Hailey-Hailey disease (HHD), or benign familial pemphigus, is an autosomal dominant genodermatosis that usually presents between the second and fourth decades of life as painful blisters and erosions in the intertriginous areas.1 It is characterized by a remitting, relapsing course, and recurrent episodes of superinfection. HHD is caused by mutations in the ATP2C1 gene.

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What this paper is about

Hailey-Hailey disease (HHD), or benign familial pemphigus, is an autosomal dominant genodermatosis that usually presents between the second and fourth decades of life as painful blisters and erosions in the intertriginous areas.1 It is characterized by a remitting, relapsing course, and recurrent episodes of superinfection. HHD is caused by mutations in the ATP2C1 gene.

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Available abstract

Hailey-Hailey disease (HHD), or benign familial pemphigus, is an autosomal dominant genodermatosis that usually presents between the second and fourth decades of life as painful blisters and erosions in the intertriginous areas.1 It is characterized by a remitting, relapsing course, and recurrent episodes of superinfection. HHD is caused by mutations in the ATP2C1 gene.

Key concepts: Hailey–Hailey disease, Genodermatosis, Intertriginous, Medicine, Dermatology, Pemphigus, Disease, Superinfection

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