2019•DOAJ (DOAJ: Directory of Open Access Journals)Open access

PURE NEURAL LEPROSY, A DIAGNOSIS NOT TO MISS IN PATIENTS PRESENTING WITH POLYNEUROPATHY

Imran Nazir Ahmad, Mutaher Zia, Muhammad Irfan Anwar

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Abstract

Leprosy is a chronic infectious disease, caused by Mycobacterium leprae. It mainly affects the peripheral nerves and skin. In pure neural or neuritic leprosy, there are no skin lesions. Hence the diagnosis is delayed, leading to deformities. It is more common in India as compared to other countries, including Pakistan. We are reporting two cases who presented with pure neural leprosy. Their diagnosis was delayed for several months, until a nerve biopsy showed typical changes of leprosy. Due to the delay in diagnosis, both developed visible deformities (grade 2 disabilities). These two cases emphasize the importance of early recognition of this type of leprosy; so as to prevent permanent crippling disabilities.

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What this paper is about

Leprosy is a chronic infectious disease, caused by Mycobacterium leprae. It mainly affects the peripheral nerves and skin. In pure neural or neuritic leprosy, there are no skin lesions. Hence the diagnosis is delayed, leading to deformities. It is more common in India as compared to other countries, including Pakistan. We are reporting two cases who presented with pure neural leprosy. Their diagnosis was delayed for several months, until a nerve biopsy showed typical changes of leprosy. Due to the delay in diagnosis, both developed visible deformities (grade 2 disabilities). These two cases emphasize the importance of early recognition of this type of leprosy; so as to prevent permanent crippling disabilities.

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Available abstract

Leprosy is a chronic infectious disease, caused by Mycobacterium leprae. It mainly affects the peripheral nerves and skin. In pure neural or neuritic leprosy, there are no skin lesions. Hence the diagnosis is delayed, leading to deformities. It is more common in India as compared to other countries, including Pakistan. We are reporting two cases who presented with pure neural leprosy. Their diagnosis was delayed for several months, until a nerve biopsy showed typical changes of leprosy. Due to the delay in diagnosis, both developed visible deformities (grade 2 disabilities). These two cases emphasize the importance of early recognition of this type of leprosy; so as to prevent permanent crippling disabilities.

Key concepts: Leprosy, Mycobacterium leprae, Medicine, Nerve biopsy, Polyneuropathy, Dermatology, Skin biopsy, Peripheral nerve

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