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2019•IOP Conference Series Materials Science and EngineeringOpen access

Synthesis, Characterization and Insilco Study of New 1,3-Oxazolone-5-(4-Cl)-one and - Oxazolone-5-(4-NO2)-one Derivatives

Hanan A. Al-Hazam, Abdulbari Mahdi Mahood

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Abstract

In this study two new compounds are prepared 1,3-Oxazolone-5-(4-Cl)-one and Oxazolone-5-(4-NO 2 )-one derivatives by a reaction of glycine with sebacoyl chloride. The two compoundswere identified and characterized by CHN, IR and 1 H-NMR Spectroscopy. Both derivativesshow different biological activity according to the program.

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In this study two new compounds are prepared 1,3-Oxazolone-5-(4-Cl)-one and Oxazolone-5-(4-NO 2 )-one derivatives by a reaction of glycine with sebacoyl chloride. The two compoundswere identified and characterized by CHN, IR and 1 H-NMR Spectroscopy. Both derivativesshow different biological activity according to the program.

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Available abstract

In this study two new compounds are prepared 1,3-Oxazolone-5-(4-Cl)-one and Oxazolone-5-(4-NO 2 )-one derivatives by a reaction of glycine with sebacoyl chloride. The two compoundswere identified and characterized by CHN, IR and 1 H-NMR Spectroscopy. Both derivativesshow different biological activity according to the program.

Key concepts: Oxazolone, Chemistry, Glycine, Organic chemistry, Biochemistry, Amino acid

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Synthesis, Characterization and Insilco Study of New 1,3-Oxazolone-5-(4-Cl)-one and - Oxazolone-5-(4-NO2)-one Derivatives — Research Paper | ScholarLens