QTL Analysis Methods
Özge Şahin, Orhan Kavuncu
Abstract
Özge Şahin, Orhan Kavuncu
Abstract
In recent years, quantitative characters have settled to a quite important place among genetic studies. The inheritance of these traits is usually achieved by multiple gene expression and by the additive and interactive effects of these genes. Therefore, the analysis methods used to understand the genetic basis of quantitative traits may be more complex than those of qualitative traits. The loci on the chromosome at which the genes controlling the genetic architecture of the quantitative traits are located are called the quantitative trait loci (QTL). There are different methods for detecting and analyzing the presence of these loci. In addition, it is possible to map the QTLs with the help of the molecular markers as a developing method thanks to today's technology. In this review, the methods of diagnosing QTL and mapping studies were analyzed.
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In recent years, quantitative characters have settled to a quite important place among genetic studies. The inheritance of these traits is usually achieved by multiple gene expression and by the additive and interactive effects of these genes. Therefore, the analysis methods used to understand the genetic basis of quantitative traits may be more complex than those of qualitative traits. The loci on the chromosome at which the genes controlling the genetic architecture of the quantitative traits are located are called the quantitative trait loci (QTL). There are different methods for detecting and analyzing the presence of these loci. In addition, it is possible to map the QTLs with the help of the molecular markers as a developing method thanks to today's technology. In this review, the methods of diagnosing QTL and mapping studies were analyzed.
Key concepts: Quantitative trait locus, Family-based QTL mapping, Genetic architecture, Biology, Inheritance (genetic algorithm), Inclusive composite interval mapping, Genetics, Gene