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2019•University journal of pre and paraclinical sciencesRequires access

MIXED GERM CELL TUMOUR - OVARY - CASE REPORT

Shanmuga Priya P R

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Abstract

Mixed germ cell tumors of ovary are malignant neoplasms of the ovary comprising of two or more types of germ cell components. The combination of various elements occurs in approximately 8 percentage of cases. The most common      combination is that of dysgerminoma with yolk sac tumor, but other combinations including teratoma, choriocarcinoma, embryonal carcinoma etc may also occur. These tumors mainly affect young girls and women of reproductive age group. Hence its identification and diagnosis assumes importance for the    treatment. Here a case of mixed germ cell tumor of ovary is presented. A 15 year old girl presented with abdominal pain, abdominal mass and irregular bleeding. MRI showed huge  pelvic mass. Tumor markers AFP, Beta HCG, LDH were elevated. Tumor was excised. Histopathological examination showed mixed germ cell tumor with components of yolk sac tumor with dysgerminoma, embryonal carcinoma, teratoma and choriocarcinoma

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Mixed germ cell tumors of ovary are malignant neoplasms of the ovary comprising of two or more types of germ cell components. The combination of various elements occurs in approximately 8 percentage of cases. The most common      combination is that of dysgerminoma with yolk sac tumor, but other combinations including teratoma, choriocarcinoma, embryonal carcinoma etc may also occur. These tumors mainly affect young girls and women of reproductive age group. Hence its identification and diagnosis assumes importance for the    treatment. Here a case of mixed germ cell tumor of ovary is presented. A 15 year old girl presented with abdominal pain, abdominal mass and irregular bleeding. MRI showed huge  pelvic mass. Tumor markers AFP, Beta HCG, LDH were elevated. Tumor was excised. Histopathological examination showed mixed germ cell tumor with components of yolk sac tumor with dysgerminoma, embryonal carcinoma, teratoma and choriocarcinoma

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Available abstract

Mixed germ cell tumors of ovary are malignant neoplasms of the ovary comprising of two or more types of germ cell components. The combination of various elements occurs in approximately 8 percentage of cases. The most common      combination is that of dysgerminoma with yolk sac tumor, but other combinations including teratoma, choriocarcinoma, embryonal carcinoma etc may also occur. These tumors mainly affect young girls and women of reproductive age group. Hence its identification and diagnosis assumes importance for the    treatment. Here a case of mixed germ cell tumor of ovary is presented. A 15 year old girl presented with abdominal pain, abdominal mass and irregular bleeding. MRI showed huge  pelvic mass. Tumor markers AFP, Beta HCG, LDH were elevated. Tumor was excised. Histopathological examination showed mixed germ cell tumor with components of yolk sac tumor with dysgerminoma, embryonal carcinoma, teratoma and choriocarcinoma

Key concepts: Choriocarcinoma, Dysgerminoma, Yolk sac, Immature teratoma, Ovary, Germ cell tumors, Teratoma, Embryonal carcinoma

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