[An analysis of the mutation in GJB2,GJB3,SLC26A4 and mtDNA12SrRNA in new born].
Feng Yih Chai, Zhao Hl, Qiu Sq
Abstract
Feng Yih Chai, Zhao Hl, Qiu Sq
Abstract
235delC is the main mutation form of GJB2 gene,while it is the hottest mutation in People. But SLC26A4 gene mutations are the main type in newborn. MtDNA 12Rrna gene mutation was found in 3 child.This genetic epidemiological study demonstrated that genetic screening is helpful for determining high risk individuals and early discovering possible late-onset hearing loss. Moreover pationts and family member can acquire more effective genetic counseling.
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235delC is the main mutation form of GJB2 gene,while it is the hottest mutation in People. But SLC26A4 gene mutations are the main type in newborn. MtDNA 12Rrna gene mutation was found in 3 child.This genetic epidemiological study demonstrated that genetic screening is helpful for determining high risk individuals and early discovering possible late-onset hearing loss. Moreover pationts and family member can acquire more effective genetic counseling.
Key concepts: Genetics, Mutation, Loss of heterozygosity, Biology, Compound heterozygosity, Genotype, Allele, Gene mutation