2011•German Medical Science (German Research Foundation)Open access
Polymorphisms in DNA repair genes modify lymphoma risk
Katja Butterbach, Odilia Popanda, Sílvia de Sanjosé, Yolanda Benavente, Nikolaus Becker, Lenka Foretová, Marc Maynadié, Pierluigi Cocco, Anthony Staines, Rudolf Kaaks, Stefanie Hieke, M. Schumacher, Paolo Boffetta, Paul Brennan, Alexandra Nieters
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Abstract
Introduction: The high risk of lymphoma among individuals affected by hereditary syndromes associated with aberrant repair of DNA double-strand breaks points towards an important role of this pathway in lymphomagenesis. Single nucleotide polymorphisms (SNPs) that affect DNA repair mechanisms can increase[for full text, please go to the a.m. URL]