Clinical Study for Mucociliary clearance of Pediatric Chronic Sinusitis after KamiHyunggyeyungotang Therapy

Background: Delayed mucociliary clearance develops the pooling of nasal secretion in the nasal cavity and is a common cause of vicious cycle of symptoms in chronic sinusitis. mucociliary clearance depends on the ciliary activity, the rheological property of the secretion and on the interaction between cilia and the mucous blanket. Objective: To demonstrate the therapeutic effect of herbal medicine (Hyunggyeyungotang) on the mucociliary transport in the chronic sinusitis using saccharine Materials and methods: Forty patients treated in our hospital between september 2000 and september 2001 were studied. Before and after therapy group are composed of twenty patients. Kamihyunggyeyungyotang was administered mainly. We analyzed the saccharine mucociliary transport time of patients. Results: 1) In the control group, the transport time is about 13.4 minutes. 2) In chronic sinusitis before Kamihyunggyeyungotang therapy, the transport time is about 27.7 minutes. 3) In chronic sinusitis after Kamihyunggyeyungotang therapy, the transport time is about 13.8 minutes. Conclusion: Delayed mucociliary transport time in chronic sinusitis is earlier after Kamihyunggyeyungotang therapy.