2010•CirculationRequires access

Abstract 15791: Myocardial Induction of Tissue Inhibitor of Matrix Metalloproteinase-4 Modifies Post Myocardial Infarction Left Ventricular Remodeling

Francis G. Spinale, Juozas A. Zavadzkas, Robert E. Stroud, William T. Rivers, Richard A. McKinney, Eileen I. Chang, Rebecca A Plyler, Shenikqua Bouges, Rupak Mukherjee

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Abstract

Background: Alterations in the balance between matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) contribute to adverse LV remodeling following myocardial infarction (MI). In pa...

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Key concepts: Medicine, Myocardial infarction, Cardiology, Ventricular remodeling, Internal medicine, Matrix metalloproteinase, Tissue inhibitor of metalloproteinase, Metalloproteinase