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2019•Journal of InstrumentationOpen access

Development of thermal neutron moderator for testing boron agents for Boron Neutron Capture Therapy (BNCT)

Go Ichikawa, Koji Tsuchida, Yoshiaki Kiyanagi, Akihisa Ishikawa, Yuho Hirata, Sachiko Yoshihashi, Kenichi Watanabe, Akira Uritani, Tsuyoshi Hamano, Ryo Ogawara, M. Suda, Kazuyo Igawa

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Abstract

We developed a thermal neutron source for performance tests of boron agents for Boron Neutron Capture Therapy (BNCT) at Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) in National Institute of Radiological Sciences, Japan. The thermal neutron flux at the experimental position was measured to be 2.18 × 10 8 n/cm 2 /s, the cadmium ratio was 9.21, and gamma ray dose rate was 2.11 Gy/h. The neutron dose rate was estimated to be 2.96 Gy/h. These values indicate that the neutron source can be applicable for tests of boron agents although application range is limited. An example of irradiation experiment is described.

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We developed a thermal neutron source for performance tests of boron agents for Boron Neutron Capture Therapy (BNCT) at Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) in National Institute of Radiological Sciences, Japan. The thermal neutron flux at the experimental position was measured to be 2.18 × 10 8 n/cm 2 /s, the cadmium ratio was 9.21, and gamma ray dose rate was 2.11 Gy/h. The neutron dose rate was estimated to be 2.96 Gy/h. These values indicate that the neutron source can be applicable for tests of boron agents although application range is limited. An example of irradiation experiment is described.

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Available abstract

We developed a thermal neutron source for performance tests of boron agents for Boron Neutron Capture Therapy (BNCT) at Neutron exposure Accelerator System for Biological Effect Experiments (NASBEE) in National Institute of Radiological Sciences, Japan. The thermal neutron flux at the experimental position was measured to be 2.18 × 10 8 n/cm 2 /s, the cadmium ratio was 9.21, and gamma ray dose rate was 2.11 Gy/h. The neutron dose rate was estimated to be 2.96 Gy/h. These values indicate that the neutron source can be applicable for tests of boron agents although application range is limited. An example of irradiation experiment is described.

Key concepts: Neutron capture, Boron, Neutron temperature, Neutron source, Neutron, Radiochemistry, Materials science, Neutron moderator

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