2002Journal of Chemical ResearchOpen access

A Novel Chalcone from Garcinia Nervosa

Mohammad Ilyas, Mehtab Perveen, Shafiullah, Syed Mohmud Ahmad

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Abstract

A novel chalcone 5′-bromo-2′-hydroxy-4,4′,6′-trimethoxy-chalcone, isoliquiritigenin-4,4′-dimethyl ether (2′-hydroxy-4,4′-dimethoxy chalcone) and 2′-hydroxy-3,4,4′,6′-tetramethoxy dihydrochalcone have been isolated from the leaves of Garcinia nervosa. Their structure have been elucidated on the basis of chemical and spectral evidences ( 1 H NMR, 13 C NMR, HMQC, NOE, IR, UV and mass spectra).

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A novel chalcone 5′-bromo-2′-hydroxy-4,4′,6′-trimethoxy-chalcone, isoliquiritigenin-4,4′-dimethyl ether (2′-hydroxy-4,4′-dimethoxy chalcone) and 2′-hydroxy-3,4,4′,6′-tetramethoxy dihydrochalcone have been isolated from the leaves of Garcinia nervosa. Their structure have been elucidated on the basis of chemical and spectral evidences ( 1 H NMR, 13 C NMR, HMQC, NOE, IR, UV and mass spectra).

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Available abstract

A novel chalcone 5′-bromo-2′-hydroxy-4,4′,6′-trimethoxy-chalcone, isoliquiritigenin-4,4′-dimethyl ether (2′-hydroxy-4,4′-dimethoxy chalcone) and 2′-hydroxy-3,4,4′,6′-tetramethoxy dihydrochalcone have been isolated from the leaves of Garcinia nervosa. Their structure have been elucidated on the basis of chemical and spectral evidences ( 1 H NMR, 13 C NMR, HMQC, NOE, IR, UV and mass spectra).

Key concepts: Chalcone, Isoliquiritigenin, Chemistry, Stereochemistry, Organic chemistry

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