ChemInform Abstract: Determination of the Absolute Configuration of Secondary Alcohols by Modified Horeau′s Method Using HPLC.
Aleš Svatoš, Irena Valterová, Anna Fábryová, Jan Vrkoč
Abstract
Aleš Svatoš, Irena Valterová, Anna Fábryová, Jan Vrkoč
Abstract
Abstract Using a modified Horeau's method, the absolute configuration of secondary alcohols can be determined by reaction with 2 equiv. of racemic 2‐phenylbutanoic anhydride, of which one enantiomer reacts preferentially with the chiral alcohol.
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Abstract Using a modified Horeau's method, the absolute configuration of secondary alcohols can be determined by reaction with 2 equiv. of racemic 2‐phenylbutanoic anhydride, of which one enantiomer reacts preferentially with the chiral alcohol.
Key concepts: Chemistry, Absolute configuration, Enantiomer, Absolute (philosophy), Alcohol, High-performance liquid chromatography, Organic chemistry, Chiral column chromatography