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ChemInform Abstract: The Enzymatic Conversion of Exomethylene Cephalosporin C into Deacetyl Cephalosporin C and the Role of Molecular Oxygen in Cephalosporin C Biosynthesis.

Jack Edward Baldwin, Robert M. Adlington, Nicholas P. Crouch, Christopher John Schofield

Abstract

Abstract Cell free extracts from Cephalosporium acremonium containing deacetoxy/deacetyl cephalosporin C synthetase activities are shown to convert exomethylene cephalosporin C (I) directly to deacetyl cephalosporin C (II), a precursor in the cephalosporin C (III) biosynthesis.

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Available abstract

Key concepts: Cephalosporin C, Cephalosporin, Chemistry, Biosynthesis, Cephalosporin Antibiotic, Enzyme, Biochemistry, Acremonium