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ChemInform Abstract: Synthesis of 2,5‐Diaryl‐Substituted Thiophenes as Helical Mimetics: Towards the Modulation of Islet Amyloid Polypeptide (IAPP) Amyloid Fibril Formation and Cytotoxicity.

Avid Hassanpour, Carole Anne De Carufel, Steve Bourgault, Pat Forgione

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Abstract

Abstract All products are investigated for their capacity of modulating IAPP amyloid fibril formation with the thioflavin T fluorescence‐based assay.

About this research paper

What this paper is about

Abstract All products are investigated for their capacity of modulating IAPP amyloid fibril formation with the thioflavin T fluorescence‐based assay.

Why it matters

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Method / approach

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Available abstract

Abstract All products are investigated for their capacity of modulating IAPP amyloid fibril formation with the thioflavin T fluorescence‐based assay.

Key concepts: Chemistry, Amyloid fibril, Amyloid (mycology), Islet, Amyloid β, Fibril, Cytotoxicity, β amyloid

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ChemInform Abstract: Synthesis of 2,5‐Diaryl‐Substituted Thiophenes as Helical Mimetics: Towards the Modulation of Islet Amyloid Polypeptide (IAPP) Amyloid Fibril Formation and Cytotoxicity. — Research Paper | ScholarLens