Ming Zhang
Abstract
The direct amination of azole C-H bonds provides a straightforward, effective access to nitrogen group containing azoles without the prefunctionalization of azoles. This review discussed the rapid advances in the direct amination of azoles; copper-catalyzed/mediated amination, acid-promoted amination, and metal-free amination are discussed.
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The direct amination of azole C-H bonds provides a straightforward, effective access to nitrogen group containing azoles without the prefunctionalization of azoles. This review discussed the rapid advances in the direct amination of azoles; copper-catalyzed/mediated amination, acid-promoted amination, and metal-free amination are discussed.
Key concepts: Amination, Chemistry, Azole, Combinatorial chemistry, Reductive amination, Organic chemistry, Catalysis, Antifungal