Use of Stabilized Phthalide Anion Annulation Reactions in Synthesis: An Update
Margaret A. Brimble, Kris Rathwell
Abstract
Margaret A. Brimble, Kris Rathwell
Abstract
Annulation of stabilized phthalide anions with Michael acceptors provides a powerful tool for the synthesis of quinoid natural products. This review details progress made in this area building on the excellent review of this reaction published in 1995. © Georg Thieme Verlag Stuttgart.
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Annulation of stabilized phthalide anions with Michael acceptors provides a powerful tool for the synthesis of quinoid natural products. This review details progress made in this area building on the excellent review of this reaction published in 1995. © Georg Thieme Verlag Stuttgart.
Key concepts: Phthalide, Annulation, Chemistry, Ion, Combinatorial chemistry, Michael reaction, Organic chemistry, Catalysis