Gingerol Derivatives from the Rhizomes of Zingiber Officinale

Two new gingerol derivatives, [8]-gingesulfonic acid (1) and [10]-gingesulfonic acid (2), were isolated from the rhizomes of Zingiber officinale, along with nine known gingerol derivatives, [6]- gingesulfonic acid (3), 1-dehydro-[6]-gingerdione (4), 1-dehydro-[8]-gingerdione (5), 1-dehydro- [10]-gingerdione (6), [6]-gingerdione (7), [10]-gingerdione (8), [6]-gingerol (9), methyl [6]-gingerdiol (10), and 6-hydroxyl-[6]-shogaol (11). Their structures were elucidated on the basis of spectral evidence and comparisons with literature data.