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ChemInform Abstract: Synthesis of Indolizines from N‐(2,2,2‐Trifluoroethyl)pyridinium Triflate. Evidence for the Generation of Pyridinium (Trifluoromethyl)methylide.

R. E. BANKS, S. N. MOHIALDIN

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Abstract

Abstract The methylide (II), formed by treatment of pyridinium triflate (I) with bases, is trapped with the acetylenes (III) to produce the dihydroindolizines (IV) which are partly dehydrogenated to form the indolizines (V).

About this research paper

What this paper is about

Abstract The methylide (II), formed by treatment of pyridinium triflate (I) with bases, is trapped with the acetylenes (III) to produce the dihydroindolizines (IV) which are partly dehydrogenated to form the indolizines (V).

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Main findings

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Available abstract

Abstract The methylide (II), formed by treatment of pyridinium triflate (I) with bases, is trapped with the acetylenes (III) to produce the dihydroindolizines (IV) which are partly dehydrogenated to form the indolizines (V).

Key concepts: Pyridinium, Chemistry, Trifluoromethanesulfonate, Dehydrogenation, Medicinal chemistry, Pyridinium Compounds, Trifluoromethyl, Organic chemistry

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ChemInform Abstract: Synthesis of Indolizines from N‐(2,2,2‐Trifluoroethyl)pyridinium Triflate. Evidence for the Generation of Pyridinium (Trifluoromethyl)methylide. — Research Paper | ScholarLens