2019JAMARequires access

Safer CAR T-Cell Therapy

Jennifer Abbasi

Open publisher page 1 citations

Abstract

None of the 25 patients with refractory B cell lymphoma who received a modified anti-CD19 chimeric antigen receptor (CAR) T-cell therapy in a phase 1 trial experienced serious neurological toxicity or cytokine-release syndrome, researchers recently reported in Nature Medicine.

About this research paper

What this paper is about

None of the 25 patients with refractory B cell lymphoma who received a modified anti-CD19 chimeric antigen receptor (CAR) T-cell therapy in a phase 1 trial experienced serious neurological toxicity or cytokine-release syndrome, researchers recently reported in Nature Medicine.

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Available abstract

None of the 25 patients with refractory B cell lymphoma who received a modified anti-CD19 chimeric antigen receptor (CAR) T-cell therapy in a phase 1 trial experienced serious neurological toxicity or cytokine-release syndrome, researchers recently reported in Nature Medicine.

Key concepts: Medicine, Chimeric antigen receptor, Cytokine release syndrome, CAR T-cell therapy, SAFER, CD19, Lymphoma, Cell therapy

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