ScholarLens Back to search
1988•ChemInformRequires access

ChemInform Abstract: Knoevenagel Reactions of Aldehydes with Carboxy Compounds. Part 1. Reactions of p‐Nitrobenzaldehyde with Active Methine Compounds.

Makoto Tanaka, Osamu Oota, Hideo Hiramatsu, Kazuyoshi Fujiwara

Open publisher page 0 citations

Abstract

Abstract The reaction of aldehyde (I) with acids (II) in the presence of Py (or another tert. amine) proceeds via a reversible formation of hydroxy intermediate (III) (isolable) which decarboxylates (rate determining step) to give compound (IV) (Hann and Lapworth mechanism).

About this research paper

What this paper is about

Abstract The reaction of aldehyde (I) with acids (II) in the presence of Py (or another tert. amine) proceeds via a reversible formation of hydroxy intermediate (III) (isolable) which decarboxylates (rate determining step) to give compound (IV) (Hann and Lapworth mechanism).

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Abstract The reaction of aldehyde (I) with acids (II) in the presence of Py (or another tert. amine) proceeds via a reversible formation of hydroxy intermediate (III) (isolable) which decarboxylates (rate determining step) to give compound (IV) (Hann and Lapworth mechanism).

Key concepts: Chemistry, Knoevenagel condensation, Aldehyde, Amine gas treating, Organic chemistry, Reaction mechanism, Medicinal chemistry, Catalysis

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
ChemInform Abstract: Knoevenagel Reactions of Aldehydes with Carboxy Compounds. Part 1. Reactions of p‐Nitrobenzaldehyde with Active Methine Compounds. — Research Paper | ScholarLens