ChemInform Abstract: Easy and General Method to Synthesize Chiral 2‐Hydroxy Acid Benzoates.
Victor S. Martı́n, Maria Teresa Nunez, Carlos Eugenio Tonn
Abstract
Victor S. Martı́n, Maria Teresa Nunez, Carlos Eugenio Tonn
Abstract
Abstract The oxiranes (I), obtained by asymmetric epoxidation of the corresponding allylic alcohols, are selectively cleaved with benzoic acid (II) in the presence of titanium tetra(isopropoxide) to form the dihydroxy benzoates (III).
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Abstract The oxiranes (I), obtained by asymmetric epoxidation of the corresponding allylic alcohols, are selectively cleaved with benzoic acid (II) in the presence of titanium tetra(isopropoxide) to form the dihydroxy benzoates (III).
Key concepts: Benzoates, Chemistry, Allylic rearrangement, Benzoic acid, Organic chemistry, Titanium, Medicinal chemistry, Catalysis